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multiple-sequence-alignments

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aaravdave / MSAffect

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MSAffect is a computational pipeline to evaluate the robustness of AlphaFold2 protein structure predictions under adversarial MSA perturbations to identify structural sensitivity and confidence shifts in neural-network-based folding.

computational-biology computational-chemistry msa perturbation multiple-sequence-alignment protein-folding alphafold perturbation-methods alphafold2 colabfold comp-bio multiple-sequence-alignments
  • Updated Sep 2, 2025
  • Python

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